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Since Tri-Solfen® was commercially launched, over 80 million lambs have been treated and over 80% of Australian wool growers are now using Tri-Solfen for their sheep. Here’s what some of them have to say…

‘We have used pain relief for two years now and seen real production gains. We are concerned for the welfare of our animals and will continue to use pain relief to ensure they get the best care.’

Clinton Wise– Wililoo Merino Stud, Woodanilling, W.A.

'It easy to see the difference pain relief makes. Before, lambs would walk away hunched up, even taking a couple of hours to walk back to the paddock. Now they run straight back to Mum and start suckling,” says Rod. “My wool is now sold under the Better Choices brand. I see this as a definite advantage. I think it will be an advantage in the long run, to both me and the industry as a whole.'

Rod Miller– Glenpaen Merino Stud, Horsham, Vic

'After being treated with pain relief my lambs were more content and less stressed. As farmers we are sincere in looking after the welfare of our animals and using pain relief demonstrates this.'

Richard Coole– Frankland, W.A.

'We have been using pain relief for the past three years. We’re impressed by reduced bleeding in the mulesing wound immediately after application. Lambs run straight back to find the ewe, which has dramatically reduced our mortality rates. Flock management, post lamb marking is easier due to the effect of pain relief and the scab healing faster.'

Ryan & Malcom O’Dea– Peepingee Merino Stud, Narrogin, W.A.

'Using pain relief eases the stress and allows lambs to mother up and move back to the paddock easier with faster weight gains.'

Kent Lummis– Waverley Downs, Gilgandra, NSW


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Advisory Board

Ian Page

Non-Executive Director

Ian is Chief Executive Officer of Dechra Pharmaceuticals, which has a 33% shareholder in Medical Ethics. He joined National Veterinary Services, Dechra’s former services business in 1989 and joined the Board of Dechra in 1997. In October 2010, Ian was appointed as Non-Executive Chairman of Sanford DeLand Asset Management.

Dr Chris Roberts

Human Wound and Regulatory Advisor

Chris has over 20 years’ line management experience of heading clinical research teams. He was previously global head of Smith & Nephew clinical support and market development, where he managed global clinical Phase II and III programmes in the management of venous and pressure ulcers.

Lieutenant Colonel Professor Steven Jeffery

Medical Specialist Advisor

Steve has over 15 years’ experience in military plastic surgery. In 2011 he was awarded the Military Civilian Partnership Award for ‘Regular of the Year’, as well as receiving the Wounds UK ‘Key Contribution’ award and the Smith and Nephew ‘Customer Pioneer of the Year’ award. He has also been awarded Fellowship of the Royal College of Surgeons of England ad eundum. He is an expert adviser to NICE Medical Technologies Evaluation Programme. Steve co-founded the Woundcare 4 Heroes charity, which is already making a big difference to the wound care of both serving and veteran personnel.

Dr Matthew Bayfield

Medical Specialist Scientific Director

Dr Matthew Bayfield, Head of Cardiothoracic Surgery, Strathfield Private Hospital and VMO Cardiothoracic Surgeon, Royal Prince Alfred Hospital.

Professor Peter Windsor

Veterinarian Research Advisor

Peter is a registered specialist veterinary surgeon in New South Wales and an emeritus Professor at Sydney University. He holds a BVSc (Hons), PhD, DVSc and diploma from the European College of Small Ruminant Health Management.

Dr Julian Braidwood

Global Regulatory Affairs Advisor

Julian has held leadership roles and managed international clinical projects with Grampian. He was previously Regulatory Affairs Manager at Novartis Animal Health. He is the Founder and Managing Director of Triveritas, where he is responsible for a team of 40 animal health specialists across the EU and the US.


N&H TOPLINE: Pain relief after disbudding improves animal welfare

June 15, 2018

There are welfare benefits for dairy calves in connection with disbudding if animals are given local anesthetic plus NSAID pain relief.

Article by Tim Lundeen, originally published 15 June 2018 on

A new precision breeding partnership has been formed to eliminate the need to dehorn dairy calves, but the multiyear project has just gotten underway, and implementation and widespread industry acceptance may take years.

According to Aarhus University in Denmark, farmers around the world use various methods to dehorn their animals. For example, in Denmark, dairy farmers may dehorn only calves that are under three months of age using only hot-iron disbudding and only after a veterinarian has given the calf an anesthetic that blocks the pain during the procedure.

Many studies have shown that disbudding hurts not only during the procedure but also for hours or days thereafter and, therefore, has a negative effect on animal welfare, Aarhus said.

The question is if additional pain relief can benefit calf welfare when the calves are disbudded using a hot iron. This is a question that the Danish Veterinary & Food Administration asked DCA—Danish Centre for Food & Agriculture at Aarhus University to elucidate.

Researchers from the Aarhus department of animal science said they have reviewed the literature in the area in order to compare the use of local anesthetic on its own with the use of a combination of local anesthetic and the group of analgesics: non-steroidal anti-inflammatory drugs (NSAIDs).

NSAIDs are a group of drugs that reduce pain, fever and inflammation and are used in people for headaches or joint pain. Veterinary options for NSAIDs or other pain relief medications may be limited by regulations.

NSAID promotes calf welfare
Based on the literature review, the Aarhus researchers concluded that there would be a welfare benefit in connection with using a combination of local anesthetic and NSAID instead of local anesthetic on its own and that this type of treatment would not lead to welfare disadvantages for the animals.

The researchers included a number of indicators based on three different approaches to animal welfare in their assessment of calf welfare following disbudding — namely, the animals’ basic health and production, the animals’ potential to live a natural life and their emotional state, i.e., whether they experience pain, fear or mutual bonding, the university said.

In their report, the researchers concluded that supplementing a local anesthetic with an NSAID provides better pain relief in the first hours and days after disbudding. Using an NSAID in combination with a local anesthetic reduces the immediate welfare consequences caused by disbudding.

More knowledge needed
The researchers pointed out that it could be beneficial to investigate precisely which NSAID and which dosage and type of administration work best in connection with disbudding.

There is also lack of precise knowledge about how long the calves experience pain after disbudding, Aarhus said. The burn lesion heals slowly. Studies indicate that the calves experience pain-related changes in sensitivity in the area surrounding the removed hornbuds for several months after disbudding, the researchers suggested, noting that experience from people is that changes in sensitivity induced by burn injuries are difficult to treat.

One of the report’s important messages, therefore, is that even if NSAID is used optimally, disbudding still remains a problem for calf welfare — no matter which of the three animal welfare approaches is taken.

The report to the Danish Veterinary & Food Administration is available (in Danish) here.

A related article “Welfare Effects of the Use of a Combination of Local Anesthesia & NSAID for Disbudding Analgesia in Dairy Calves — Reviewed Across Different Welfare Concerns” was published in the journal Frontiers in Veterinary Science.