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Since Tri-Solfen® was commercially launched, over 150 million lambs have been treated and over 80% of Australian wool growers are now using Tri-Solfen for their sheep. Here’s what some of them have to say…

‘We have used pain relief for two years now and seen real production gains. We are concerned for the welfare of our animals and will continue to use pain relief to ensure they get the best care.’

Clinton Wise– Wililoo Merino Stud, Woodanilling, W.A.

'It easy to see the difference pain relief makes. Before, lambs would walk away hunched up, even taking a couple of hours to walk back to the paddock. Now they run straight back to Mum and start suckling,” says Rod. “My wool is now sold under the Better Choices brand. I see this as a definite advantage. I think it will be an advantage in the long run, to both me and the industry as a whole.'

Rod Miller– Glenpaen Merino Stud, Horsham, Vic

'After being treated with pain relief my lambs were more content and less stressed. As farmers we are sincere in looking after the welfare of our animals and using pain relief demonstrates this.'

Richard Coole– Frankland, W.A.

'We have been using pain relief for the past three years. We’re impressed by reduced bleeding in the mulesing wound immediately after application. Lambs run straight back to find the ewe, which has dramatically reduced our mortality rates. Flock management, post lamb marking is easier due to the effect of pain relief and the scab healing faster.'

Ryan & Malcom O’Dea– Peepingee Merino Stud, Narrogin, W.A.

'Using pain relief eases the stress and allows lambs to mother up and move back to the paddock easier with faster weight gains.'

Kent Lummis– Waverley Downs, Gilgandra, NSW


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Advisory Board

Ian Page

Non-Executive Director

Ian is Chief Executive Officer of Dechra Pharmaceuticals, which has a 33% shareholder in Medical Ethics. He joined National Veterinary Services, Dechra’s former services business in 1989 and joined the Board of Dechra in 1997. In October 2010, Ian was appointed as Non-Executive Chairman of Sanford DeLand Asset Management.

Dr Chris Roberts

Human Wound and Regulatory Advisor

Chris has over 20 years’ line management experience of heading clinical research teams. He was previously global head of Smith & Nephew clinical support and market development, where he managed global clinical Phase II and III programmes in the management of venous and pressure ulcers.

Lieutenant Colonel Professor Steven Jeffery

Medical Specialist Advisor

Steve has over 15 years’ experience in military plastic surgery. In 2011 he was awarded the Military Civilian Partnership Award for ‘Regular of the Year’, as well as receiving the Wounds UK ‘Key Contribution’ award and the Smith and Nephew ‘Customer Pioneer of the Year’ award. He has also been awarded Fellowship of the Royal College of Surgeons of England ad eundum. He is an expert adviser to NICE Medical Technologies Evaluation Programme. Steve co-founded the Woundcare 4 Heroes charity, which is already making a big difference to the wound care of both serving and veteran personnel.

Dr Matthew Bayfield

Medical Specialist Scientific Director

Dr Matthew Bayfield, Head of Cardiothoracic Surgery, Strathfield Private Hospital and VMO Cardiothoracic Surgeon, Royal Prince Alfred Hospital.

Professor Peter Windsor

Veterinarian Research Advisor

Peter is a registered specialist veterinary surgeon in New South Wales and an emeritus Professor at Sydney University. He holds a BVSc (Hons), PhD, DVSc and diploma from the European College of Small Ruminant Health Management.

Dr Julian Braidwood

Global Regulatory Affairs Advisor

Julian has held leadership roles and managed international clinical projects with Grampian. He was previously Regulatory Affairs Manager at Novartis Animal Health. He is the Founder and Managing Director of Triveritas, where he is responsible for a team of 40 animal health specialists across the EU and the US.


Animal welfare: No going back on pain relief

July 18, 2019
Original article by Mark Phelps for Queensland Country Life

BRISBANE Valley beef producer Ben Drynan says there is no going back.

The inclusion of pain relief as a routine part of animal husbandry practices including dehorning and castration is here to stay.

Not only had the use of Trisolfen resulted in better production outcomes, but he and his family simply “felt better” about how their animals were being treated, he said.

“Pain relief has become an essential part of how we process our calves because we want to do everything we can in terms of animal welfare,” Mr Drynan said.

“The big advantage we see, apart from the immediate pain relief, is the calves mother up much faster and are drinking again if they have been treated with Trisolfen.

Pain relief has become an essential part of how we process our calves because we want to do everything we can for our animals. – Ben Drynan, Gallinani, Esk

“The value of preventing mis-mothering and saving even just one calf is a huge gain.

“The cost benefit really stacks up.”

Initially developed to treat lambs after mulesing, Trisolfen is a pain relieving and wound healing formulation that has short term and long term analgesia, antiseptics, reduces blood loss and coats the wound.

The off-the-shelf product was quickly adopted by the cattle industry when its benefits in promoting calf health were recognised.

The Drynans run about 550 Charolais type breeders on their 3650 hectare property Gallinani at Esk. The business focuses on producing export weight steers as well as feeder steers.

Mr Drynan was first exposed to Trisolfen when local rural supply company Northern AgriServices in Toogoolawah asked him to host a field day showcasing the Bayer product.

“Seeing how the product was applied particularly for the castration gave me a lot of confidence,” Mr Drynan said.

“There is some technique required but nothing too complicated.”

In addition to pain relief, the Drynans treat their calves with the long acting parasiticideCydectin LA and the trace mineral booster Multimin.

ESI established

AgForce cattle president Will Wilson said a barrier to the use of Trisolfen had been reduced with the recent announcement of an 90 day export slaughter interval by the Australian Pesticides and Veterinary Medicines Authority.

“I don’t know of anyone who has used Trisolfen and not continued to use it,” Mr Wilson said.

“And often they become pretty vocal advocates.

“When consumers start asking questions about animal welfare we need to listen.

“We need to understand ways we can use pain relief and how to implement into our programs on the basis it is of value to consumers and of value to producers.”

Overwhelming response

Bayer northern Australia area manager Mick O’Grady said the response to Trisolfen had been overwhelming.

“It’s pretty obvious that beef producers are at the forefront of doing what needs to be done for the future of the industry,” Mr O’Grady said.

Bayer manufactures Trisulfen under license from Australian company Animal Ethics.

“The (Australian Beef) sustainability framework is in place and includes a strong endorsement of pain relief, which has received a very positive reception.

“From a producer perspective we now have a product in Trisolfen that provides immediate pain relief, minimises bleeding, reduces infection, and promotes faster wound healing.”

Bayer, which manufactures Trisolfen under license from Australian company Animal Ethics, has formulated a distinctive blue gel, which has an 18 month shelf life.

It is described as best suited to calves aged six to eight weeks and is designed to provide pain relief for 24 to 36 hours. It costs between about a $1 and $1.50 to treat each animal.

Ongoing development

The McDonald family at Cloncurry has been using Trisolfen in its 175,000 head cattle herd since trials began in 2012, initiated by beef industry leader, the late Zanda McDonald.

MDH chief financial officer Julie McDonald said during that time Trisolfen had been adapted to improve its application and to suit the often harsh environment found inside cattle yards.

“For the past couple of years, we have used it across the herd on all calves and weaners – about 25,000 animals a year, and this year will be no exception,” Ms McDonald said.

“Good animal welfare practices have always been, and continue to be, central to our operation.

“The use of pain relief in this way benefits the animals by reducing pain, stress, and the calves go back onto their mothers more quickly.”

Ms McDonald said staff performing the procedures also found it less stressful.

“The industry as a whole benefits from the use of pain relief as these practices are not always palatable to people who were not familiar with the need to perform some of these procedures,” she said.

“As a company with a branded product, we talk to our customers about our supply chain management including our animal welfare husbandry credentials.

“Pain relief is a big part of that.

“Consumers expect their food to have a good story, and we are aware that it doesn’t take much to damage a brand and a reputation.”

Ms McDonald said there were commercial benefits from pain free animals.

“They are performing better in all aspects of their production,” she said.

“This begins from when they are born, so any day when they are not performing and gaining, this is a backward step that can effect the management of the supply chain.”

Australian Agricultural Company said it had a policy of providing mandatory pain relief for any surgical procedure.

“Trisolfen was chosen to provide pain relief following extensive and robust testing and we are happy with the results so far,” a spokesperson for AACo said.

“The welfare of our animals is a key part of our sustainability program.

“Our customers want to know that our animals live good lives, free of unnecessary pain, which is why we are also pursuing our poll program, with the aim of removing practices such as dehorning.”

Literature suggests calves undergoing typical animal husbandry procedures can lose up to 650 grams a day for 10 days in body weight, compared to calves that receive pain relief.

The product is also being used to treat foot and mouth disease in South East Asia, following trial work by Emeritus Professor Peter Windsor from The University of Sydney.

That trial work shows cattle and buffalo suffering from painful foot and mouth lesions caused by FMD were able to return to eating after two to three days and were cured in five to six days.

In addition to sheep and cattle, Trisolfen is also being prescribed by vets for horses. Gin Gin vet Andrew Marland, Vet Cross, said Trisolfen had proven an effective treatment under some circumstances.

“The wounds I have selected are those in areas that are difficult to bandage or on horses that are fractious or aren’t really amenable to bandaging,” Dr Marland said.